Metabolism in Bone
Development and Disorders
Our lab aims to characterize the metabolic requirements for skeletal cell function in health and disease
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Our latest news
Here you can see our most recent news items.

The MeBoDD lab recently published two manuscripts! In the first, Shauni Loopmans and colleagues investigated how culturing skeletal stem and progenitors in hypoxia rewires their metabolic profile. This study was published in the Journal of Bone and Mineral Research, and you can read it here: https://academic.oup.com/jbmr/article/39/2/150/7516972?login=true . Congratulations! In the second, published in Nature Reviews in Endocrinology, we provide an overview of the current knowledge on skeletal cell metabolism and how it regulates their function during bone development and disease. For more reading: https://www.nature.com/articles/s41574-024-00969-x

The abstract of Karina Geurtzen was selected for a plenary oral presentation at the 2023 ECTS meeting in Liverpool, UK and at 2024 Keystone Symposium on Tumor Metabolism in Banff, Canada. Here, she presented how mitochondrial respiration in breast tumor cells drives bone metastasis. Congratulations!!